We leverage our mass spectrometry systems for absolute quantitation of proteins and proteoforms of interest.
Sapient’s offers targeted proteomics using mass spectrometry to provide quantitative measures of proteins and PTMs via direct peptide sequencing. This provides not one, but multiple peptide-level measurements per protein for high specificity of identification.
We can most often provide an off-the-shelf assay for your protein of interest and rapidly optimize it to your specific study demands.
Our high throughput systems can make the same measure across tens to thousands of samples with reproducible high specificity.
We can target analyses among >6,000 proteins and PTMs in plasma and >12,000 in cells and tissue, including thousands of biologically important exosomal and membrane-bound proteins.
You can also filter our measurable proteins by signaling pathways, biological processes, and phenotypic associations to identify assays that could inform your study.
Don’t see your protein of interest? We also perform custom assay development including for difficult-to-measure proteins and proteoforms.
Innovative new drug modalities are now able to target disease-modifying proteins once considered too challenging to reach. Sapient’s expansive protein assay menu allows you to go beyond the well-characterized targets for novel discovery of druggable proteins.
For questions or to discuss a specific project, we encourage you to book a time to talk to our scientific team.
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10421 Wateridge Circle, Suite 100
San Diego, CA 92121
discover@sapient.bio
858.290.7010
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