S14L1

SEC14-like protein 1; Isoform 3 of SEC14-like protein 1; Isoform 2 of SEC14-like protein 1

May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of RIGI, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of RIGI with MAVS/IPS1, an important step in signal propagation (PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters (PubMed:17092608). {ECO:0000269|PubMed:17092608, ECO:0000269|PubMed:23843640}.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • SEC14L1

UniProt ID

  • Q92503
  • Q92503-3
Off-the-shelf

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