Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2 (PubMed:19000823). Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity). {ECO:0000250|UniProtKB:Q8VDQ1, ECO:0000269|PubMed:19000823}.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • PTGR2

UniProt ID

  • Q8N8N7

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