Plasma protease C1 inhibitor; Isoform 3 of Plasma protease C1 inhibitor; Isoform 2 of Plasma protease C1 inhibitor;Plasma protease C1 inhibitor

Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. {ECO:0000269|PubMed:8495195}.

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol


UniProt ID

  • P05155
  • P05155-3

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