COTL1

Coactosin-like protein

Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.

Associated with:

Alanine Transaminase
Albumin
Alkaline Phosphatase
Alzheimers
Anemia
Angina Pectoris
Arteriosclerosis
Aspartate Transaminase
Asthma
Atrial Fibrillation
B12
Basophils
BMI
C Reactive Protein
Calcium
Calcium Albumin Ratio
Cancer
Chronik Kidney Diesase
Coronary Artery Disease
Creatinine
Diastolic Blood Pressure
Eosinophils
Erythrocyte Sedimentation Rate
Estimated Glomerular Filtration Rate
Folate
Gamma Glutamyltransferase
Glucose
Gout
Granulocytes
HbA1c
Heart Failure
Heartrate
Hematocrit
Hemoglobin
High Density Lipoprotein Cholesterol
Hypertension
IgA
Iron
Kidney Cancer
Kidney Failure
Lactate Dehydrogenase
Liver Cirrhosis
Low Density Lipoprotein Cholesterol
Lung Cancer
Lymphocytes
Metabolic Acidosis
Metabolic Syndrome
Monocytes
Myelodysplastic Syndrome
Myocardial Infarction
Neutrophils
Phneumonia
Plasma Prothrombin Time
Platelet
Potassium
Red Blood Cell Count
Renal Tubulopathies
Respiratory Alkalosis
Severe Obesity (BMI > 35)
Systemic Lupus
Systolic Blood Pressure
Testosterone
Total Cholesterol
Transferrin Saturation
Triglyceride
Type 2 Diabetes
Urea
Uric Acid
Urine Glucose
Urine Protein
Vitamin D
Weight
White Blood Cell

Matrix Type

Plasma
Tissue/Cells

Gene Symbol

COTL1

UniProt ID

Q14019

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COTL1

Coactosin-like protein

Associated with:

Matrix Type

Gene Symbol

UniProt ID

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