ARAP1

Isoform 1 of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; Isoform 7 of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; Isoform 2 of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; Isoform 5 of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; Isoform 3 of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1;Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; Isoform 4 of Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1;Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity).

Matrix Type

Plasma
Tissue/Cells

Gene Symbol

ARAP1

UniProt ID

Q96P48
Q96P48-2
Q96P48-3
Q96P48-4
Q96P48-5
Q96P48-7

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ARAP1

Matrix Type

Gene Symbol

UniProt ID

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