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GCH1

Isoform GCH-4 of GTP cyclohydrolase 1; Isoform GCH-2 of GTP cyclohydrolase 1; Isoform GCH-3 of GTP cyclohydrolase 1;GTP cyclohydrolase 1

Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • GCH1

UniProt ID

  • P30793
  • P30793-3
  • P30793-4
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