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DOT1L

Isoform 2 of Histone-lysine N-methyltransferase, H3 lysine-79 specific;Histone-lysine N-methyltransferase, H3 lysine-79 specific

Histone methyltransferase. Methylates ‘Lys-79’ of histone H3. Nucleosomes are preferred as substrate compared to free histones (PubMed:12123582). Binds to DNA (PubMed:12628190).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • DOT1L

UniProt ID

  • Q8TEK3
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