AP1S3

Isoform 4 of AP-1 complex subunit sigma-3; Isoform 4 of AP-1 complex subunit sigma-3;AP-1 complex subunit sigma-3; Isoform 2 of AP-1 complex subunit sigma-3; Isoform 3 of AP-1 complex subunit sigma-3

Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking (PubMed:24791904).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • AP1S3

    UniProt ID

    • Q96PC3
    • Q96PC3-3
    • Q96PC3-4

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