Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro) (PubMed:11473582). Also acts as a transcriptional regulator, binding to the consensus sequence 5′-GNTGCATG-3′ following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • DNTTIP1

    UniProt ID

    • Q9H147

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