SELPL

P-selectin glycoprotein ligand 1; Isoform 2 of P-selectin glycoprotein ligand 1;P-selectin glycoprotein ligand 1

A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture. {ECO:0000269|PubMed:11566773, ECO:0000269|PubMed:12403782}.; (Microbial infection) Acts as a receptor for enterovirus 71. {ECO:0000269|PubMed:19543284}.

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • SELPLG

UniProt ID

  • Q14242
Off-the-shelf

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