SDK2

Isoform 3 of Protein sidekick-2;Protein sidekick-2; Isoform 4 of Protein sidekick-2

Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion. Acts by promoting formation of synapses between two specific retinal cell types: the retinal ganglion cells W3B-RGCs and the excitatory amacrine cells VG3-ACs. Formation of synapses between these two cells plays a key role in detection of motion. Promotes synaptic connectivity via homophilic interactions.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • SDK2

UniProt ID

  • Q58EX2
  • Q58EX2-4
Off-the-shelf

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