An ATP-dependent DNA helicase which unwinds dsDNA with a 3′-overhang in a 3′-5′ direction (PubMed:28653661). Does not unwind more than 18 bp of dsDNA (PubMed:28653661). May modulate chromosome segregation. The N-terminal domain (residues 1-54) binds DNA Y-shaped DNA better than ss- or dsDNA (PubMed:22730300). The core helicase domain binds ssDNA (PubMed:22730300, PubMed:28653661). {ECO:0000269|PubMed:15317757, ECO:0000269|PubMed:22730300, ECO:0000269|PubMed:28653661}.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • RECQL4

UniProt ID

  • O94761
Off-the-shelf

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