PWP3A

PWWP domain-containing DNA repair factor 3A; Isoform 3 of PWWP domain-containing DNA repair factor 3A; Isoform 2 of PWWP domain-containing DNA repair factor 3A

Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. {ECO:0000269|PubMed:20347427}.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • PWWP3A

UniProt ID

  • Q2TAK8
  • Q2TAK8-3
Off-the-shelf

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