GLUT4

Isoform 2 of Solute carrier family 2, facilitated glucose transporter member 4;Solute carrier family 2, facilitated glucose transporter member 4

Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • SLC2A4

UniProt ID

  • P14672
Off-the-shelf

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