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DPH7

Diphthine methyltransferase

Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • DPH7

    UniProt ID

    • Q9BTV6
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