COX20

Cytochrome c oxidase assembly protein COX20, mitochondrial; Isoform 2 of Cytochrome c oxidase assembly protein COX20, mitochondrial;Cytochrome c oxidase assembly protein COX20, mitochondrial

Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:23125284). Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme (PubMed:24403053).

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • COX20

    UniProt ID

    • Q5RI15

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