CCD78

Coiled-coil domain-containing protein 78; Isoform 6 of Coiled-coil domain-containing protein 78; Isoform 5 of Coiled-coil domain-containing protein 78; Isoform 3 of Coiled-coil domain-containing protein 78; Isoform 2 of Coiled-coil domain-containing protein 78; Isoform 4 of Coiled-coil domain-containing protein 78

Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase. Essential for centriole amplification and is required for CEP152 localization to the deuterosome.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • CCDC78

    UniProt ID

    • A2IDD5
    • A2IDD5-3
    • A2IDD5-4
    • A2IDD5-5
    • A2IDD5-6

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