ZFAN6

Isoform 2 of AN1-type zinc finger protein 6;AN1-type zinc finger protein 6

Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of ‘Lys-48’-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • ZFAND6

UniProt ID

  • Q6FIF0

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