PLCB1

Isoform B of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5-bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors (PubMed:9188725). Regulates the function of the endothelial barrier.

Associated with:

Alanine Transaminase
Alkaline Phosphatase
Angina Pectoris
Anxiety
Arteriosclerosis
Asthma
Basophils
BMI
C Reactive Protein
Calcium
Cancer
Colon Cancer
Colorectal Cancer
Coronary Artery Disease
Creatinine
Depression
Diastolic Blood Pressure
Eosinophils
Erythrocyte Sedimentation Rate
Essential Thrombocythemia
Estimated Glomerular Filtration Rate
Ferritin
Fibromyalgia
Folate
Gamma Glutamyltransferase
Granulocytes
HbA1c
Heartrate
Hematocrit
Hemoglobin
High Density Lipoprotein Cholesterol
Hypertension
Leukocytes
Liver Cirrhosis
Low Density Lipoprotein Cholesterol
Lymphocytes
Metabolic Syndrome
Monocytes
Myeloproliferative Neoplasm
Myocardial Infarction
Neuropathic Pain
Neutrophils
Panic Disorder
Phosphate
Platelet
Potassium
Prostate Cancer
Red Blood Cell Count
Reticulocytes
Severe Obesity (BMI > 35)
Stomach Cancer
Systolic Blood Pressure
Total Cholesterol
Total Lean Muscle
Triglyceride
Type 2 Diabetes
Urea
Uric Acid
Vitamin D
Waist Circumference
Waist Hip Ratio
Weight
White Blood Cell
Whole Body Fat
GPCR Signaling
JNK Signaling
PI3K/AKT/mTOR Signaling

Matrix Type

Tissue/Cells

Gene Symbol

PLCB1

UniProt ID

Q9NQ66

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PLCB1

Isoform B of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Associated with:

Matrix Type

Gene Symbol

UniProt ID

Request the PLCB1 Assay

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