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ORC3

Origin recognition complex subunit 3; Isoform 2 of Origin recognition complex subunit 3;Isoform 2 of Origin recognition complex subunit 3

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • ORC3

    UniProt ID

    • Q9UBD5
    • Q9UBD5-2
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