NHRF2

Na(+)/H(+) exchange regulatory cofactor NHE-RF2;Isoform 2 of Na(+)/H(+) exchange regulatory cofactor NHE-RF2

Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3 (PubMed:18829453). May also act as scaffold protein in the nucleus.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • NHERF2

    UniProt ID

    • Q15599
    • Q15599-2

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