E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487). Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • HECW2

UniProt ID

  • Q9P2P5

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