Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • COL3A1

UniProt ID

  • P02461

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