VATF

Isoform 2 of V-type proton ATPase subunit F;V-type proton ATPase subunit F

Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • ATP6V1F

UniProt ID

  • Q16864

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