Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:20095964, PubMed:29726814, PubMed:30139744, PubMed:35051376, PubMed:8646775, PubMed:9417057, PubMed:9930701). May be operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors (PubMed:8646775).
