Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696). Required for localization of CUL7 to the centrosome (PubMed:24793695).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • CCDC8

    UniProt ID

    • Q9H0W5

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