F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • CAPZA2

    UniProt ID

    • P47755

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