The Omics Brief | Novel Findings from Deep Metabolomics Analysis in Population Scale Studies

We touch on the key highlights related to methods used & discoveries made in our published study across >26K samples.

NULISAseq™ Mouse Panel 120

To measure 120+ cytokines, chemokines, and immune- & neurology-related proteins from less than 25 μL of sample input.

Enhancing Omics Data Integrity: A Principled Approach to PCA-Based Quality Assessment

Why PCA quality assessment workflows are critical to generating credible insights from high-dimensional omics data.

Turning back the metabolic aging clock

See how we used population-scale rLC-MS metabolomics data to develop an ML-based model to predict biological aging.

Sapient publishes breakthrough rLC-MS metabolomics study in over 26,000 samples, revealing metabolic aging clock and disease insights

Detailing the rLC-MS method & its use to predict clinically relevant physiological states at scale in human populations.

Rapid Liquid Chromatography-Mass Spectrometry (rLC-MS) for Deep Metabolomics Analysis of Population Scale Studies

This breakthrough mass spectrometry metabolomics study in >26,000 samples led to development of a metabolic aging clock.

Clean Metadata, Credible Insights: The Critical Role of Diligent Metadata Preprocessing

Why careful metadata preprocessing is key ensure insights derived from downstream analysis are accurate & reproducible.

Beyond DNA and RNA: Exposing What Sequencing Misses in Target ID and Biomarker Discovery

Why proteomics is critical to move beyond traditional known targets & biomarkers with mapping of non-canonical proteins.

Smart Biotech Scientist Podcast: “Multi-Omics Begins with ‘Why'” [Part 2]

Discussing how omics studies can answer more of the fundamental questions that drive successful drugs to market.

Trimming time: metabolomics insights to speed development of GLP-1 therapies

How metabolite biomarkers can speed GLP-1 agonist time-to-market & drive competitive advantages via novel insights.