Immune‑mediated diseases are driven by highly dynamic biological processes. Across autoimmune, inflammatory, and immune‑dysregulated conditions, patients with similar diagnoses, genetics, or clinical lab values often exhibit fundamentally different immune states, disease trajectories, and therapeutic responses.
Sapient’s multi‑omics services for immunology are designed to resolve this complexity. By integrating proteomic, cytokine, metabolomic, and lipidomic profiling with clinical context, we enable a systems‑level view of immune biology – revealing functional mechanisms and dynamic biomarkers.
What immune pathways are actively driving disease in patients?
How do metabolic and inflammatory pathways shape immune states?
Why do individuals with similar diagnoses respond differently to the same therapy?
How does immune biology change dynamically over time in response to exposures?
Discover immune biomarkers associated with disease activity and progression by measuring dynamic proteins, metabolites, and lipids linked to immune response and inflammation.
Identify biomarkers that read out treatment response and mechanism of action, enabling early detection of subtle molecular changes that precede clinical disease or follow therapeutic intervention.
Uncover biologically distinct immune subtypes by integrating molecular profiles with clinical and phenotypic features – for stratification rooted in functional biology and improved with multi-biomarker signatures.
We’ve innovated our methods to profile the dynamic biology of immune-mediated diseases at a new depth and scale, capturing proteins, metabolites, and lipids that change with inflammatory and autoimmune conditions and treatments. These offerings include:
See how Sapient’s mass spectrometry-based methods can be applied to read out early and subtle changes in immune cell populations, their activation and function, and dynamic response in the setting of autoimmune disease and treatment.
DynamiQ is Sapient’s longitudinal molecular‑clinical data resource, built from tens of thousands of deeply phenotyped human samples. For immunology programs, DynamiQ enables:
Resolve distinct immune states within shared diagnoses via deep phenotyping.
Layer your data and ours to orthogonally validate findings and extend discoveries.
Anchor discoveries in real-world patient data to build confidence for translation.
