Dynamic Biomarkers for Deep Immune Phenotyping in Autoimmune Disease

Autoimmune diseases present with a wide range of clinical symptoms, severity, and therapeutic response, complicating the diagnosis and treatment of patients. Small molecule biomarkers read out dynamic changes that occur with immune system activation, dysregulation, and response to drug exposure.

In this webinar, we will discuss how high throughput mass spectrometry-based methods can be applied to broadly assay thousands of metabolites and lipids per sample at a time, to read out early and subtle changes in immune cell populations, their activation and function, and dynamic response in the setting of autoimmune disease and treatment.

You will learn:

• Why discovery of dynamic small molecule biomarkers in the setting of autoimmunity can drive greater understanding of disease mechanisms and subtypes, patient response, and drug safety
• How emerging technologies are now enabling rapid measure of dynamic small molecule biomarkers at population level scale
• How integration of small molecule biomarkers with other dynamic readouts, including cytokine measures, can inform development of safer, more efficacious treatments that target the underlying pathways of autoimmune diseases