GFRA1

Isoform 2 of GDNF family receptor alpha-1;GDNF family receptor alpha-1

Coreceptor for GDNF, a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake (PubMed:10829012, PubMed:31535977). GDNF-binding leads to autophosphorylation and activation of the RET receptor (PubMed:31535977).

Associated with:

Acute Kidney Injury
Acute Renal Failure
Alanine Transaminase
Albumin
Alkaline Phosphatase
Amylase
Angina Pectoris
Apolipoprotein A
Apolipoprotein B
Arterial Embolism And Thrombosis
Arteriosclerosis
Arthrosis
Aspartate Transaminase
Atherosclerosis
Atrial Fibrillation
B12
Basal Cell Skin Cancer
Basal Metabolic Rate
Basophils
BMI
Breast Cancer
Bronchiectasis
C Reactive Protein
Calcium
Calcium Albumin Ratio
Cancer
Cardiac Arrest
Cellulitis
Cerebral Infarction
Cerebrovascular Diseases
Chloride
Chrohns Disease
Chronic Ischaemic Heart Disease
Chronic Nephritic Syndrome
Chronic Obstructive Pulmonary Disease
Chronic Renal Failure
Chronik Kidney Diesase
Colon Cancer
Colorectal Cancer
Coronary Artery Disease
Creatinine
Cystatin C
Daily Pain
Decubitus Ulcer
Dementia
Depression
Diaphragmatic Hernia
Diastolic Blood Pressure
Direct Bilirubin
Disorder Of Lipoprotein Metabolism
Diverticular Disease
Dorsalgia
Duodenal Ulcer
Emphysema
Endometrial Cancer
Eosinophils
Erythrocyte Sedimentation Rate
Estimated Glomerular Filtration Rate
Ferritin
Fibromyalgia
Fluid Intelligence
Folate
FT3 FT4 Ratio
Gallstones
Gamma Glutamyltransferase
Gastritis And Duodenitis
Gastroesophageal Reflux
Gestational Diabetes
Glomerular Disorders
Glucose
Gout
Granulocytes
Haematuria
HbA1c
Heart Failure
Heartrate
Height
Hematocrit
Hemiplegia
Hemoglobin
Hepatic Failure
High Density Lipoprotein Cholesterol
Hip Osteoarthritis
Hypertension
Hypotension
IgA
Insomnia
Iron
Kidney Cancer
Kidney Failure
Kidney Stones
Knee Osteoarthritis
Lactate Dehydrogenase
Leukocytes
Liver Cirrhosis
Low Density Lipoprotein Cholesterol
Lymphocytes
Metabolic Acidosis
Metabolic Syndrome
Monocytes
Mononeuropathy
Myocardial Infarction
Nephritis
Neutrophils
Oesophageal Varices
Oestradiol
Peripheral Vascular Disease
Peritonitis
Phlebitis And Thrombophlebitis
Phosphate
Physical Activity
Plasma Prothrombin Time
Platelet
Pleural Effusion
Pneumonia
Polyneuropathy
Potassium
Prostate Cancer
Pulmonary Embolism
Pulmonary Oedema
Red Blood Cell Count
Reduced Echo Ejection Fraction
Renal Failure
Respiratory Alkalosis
Respiratory Failure
Reticulocytes
Rheumatoid Arthritis
Septicaemia
Severe Obesity (BMI > 35)
Sleep Apnea
Sleep Disorders
Sodium
Spine Bone Mineral Density
Spondylosis
Stroke
Systemic Lupus
Systolic Blood Pressure
Testosterone
Thyroid FT3
Thyroid FT4
Total Bilirubin
Total Cholesterol
Total Fat
Total Lean Muscle
Transferrin Saturation
Triglyceride
Type 2 Diabetes
Urea
Uric Acid
Urine Glucose
Urine Protein
Vascular Dementia
Vitamin D
Waist Circumference
Waist Hip Ratio
Weight
White Blood Cell
Whole Body Fat
Early Estrogen Response

Matrix Type

Tissue/Cells

Gene Symbol

GFRA1

UniProt ID

P56159

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GFRA1

Isoform 2 of GDNF family receptor alpha-1;GDNF family receptor alpha-1

Associated with:

Matrix Type

Gene Symbol

UniProt ID

Request the GFRA1 Assay

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