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EWS

RNA-binding protein EWS; Isoform 5 of RNA-binding protein EWS; Isoform EWS-B of RNA-binding protein EWS; Isoform 3 of RNA-binding protein EWS; Isoform 6 of RNA-binding protein EWS

Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

    Matrix Type

    Gene Symbol

    UniProt ID

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