Identify and validate the most
biologically relevant small molecule biomarkers faster than ever before.
Through our proprietary rapid liquid chromatography (rLC) coupled to high resolution ion mobility mass spectrometry, Sapient can measure thousands of small molecules per sample,
across thousands of samples at a time. Chemistries captured include but are not limited to:
Our discovery metabolomics and lipidomics screening leads us to the most biologically relevant signals, including molecules yet to be mapped.
Using our expansive library of >10,000 chemical reference standards, we can assign Tier 1 identifications (meeting MSI Tier 1 reporting criteria) for over 1,000 metabolites and lipids that are routinely measured in human blood.
We can also use this library and our database of over 6 million MS2 spectra for 600,000 compounds to perform matches against, significantly amplifying our ability to structurally elucidate and confidently annotate unknown molecules.
Our next-generation mass spectrometry systems have an analytical cycle time of <1 minute, allowing us to process over 5,000 cellular, preclinical, and human samples per day.
That means you can have confidence in our capacity to generate results with rapid turnaround, even for large-scale studies.
Given the dynamic complexity of small molecule biomarkers, it is critical to understand how they behave across populations of individuals representing different lifestyles, geographies, disease states, and timepoints.
Sapient’s Human Biology Database enables just that. Comprised of multi-omics data from 56,000+ biosamples and linked with phenotypic and real-world data, including 10-30 years of clinical outcomes across patients, it allows us to:
Submit a question or project request via the form, or click the button below to schedule a meeting with our scientists.
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10421 Wateridge Circle, Suite 100
San Diego, CA 92121
discover@sapient.bio
858.290.7010