Overview | January 14, 2026
What Discovery Metabolomics Reveals About Human Biology
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Download NowThe ability to uncover novel human biology is key to discovery. Metabolomics research has increasingly come into focus to as a way to uncover new disease mechanisms, risk states, and biological heterogeneity, as metabolomics data can explain phenotypic variability among individuals who share similar genetic backgrounds, clinical diagnoses, or lab values.
Discovery metabolomics adds new layers of insights that cannot be obtained through genomics alone, which explains risk but not necessarily actual state, or with proteomics which captures regulation but not exposure or flux. Nontargeted metabolomics reveals how biological processes manifest in humans, rather than how they are inferred or predicted, and how exposure signals can modify disease risk.
Sapient powers innovative metabolomics research with scalable approaches to measure functional metabolic states in humans.
With unmatched metabolome coverage and rapid, high-throughput workflows, we enable metabolite and lipid biomarker discovery at an entirely new speed and scale.
Download the white sheet to explore key use cases for discovery metabolomics, and specifically how Sapient’s workflows – which capture >15,000 metabolites and lipids per plasma sample – enables researchers to:
- Define biologically distinct human subpopulations
- Separate disease presence from disease mechanism
- Reveal system-wide effects invisible to tissue-specific markers
- Capture environmental, microbial, and drug-related biology simultaneously
From identifying previously unrecognized pathways driving disease, to tracking how exposures modify genetic risk, to elucidating metabolic signals that precede clinical disease, the insights enabled through metabolomics research will power the next advances in precision medicine.
Sapient’s best-in-class discovery metabolomics offering maximizes your discovery potential and ability to uncover such critical novel findings that can help resolve heterogeneity, mechanism, or health / disease trajectory that other omics have not.