Transcription factor that binds to the consensus sequence 5′-TCCTCCC-3′ and acts as a transcriptional repressor (PubMed:32051553). Binds to the promoter region of SIX3 and recruits other proteins involved in chromatin modification and transcriptional corepression, resulting in methylation of the promoter and transcriptional repression (PubMed:32051553). Acts as a transcriptional repressor of HS3ST1 and HS3ST3A1 via binding to gene promoter regions (PubMed:32277030).

    Matrix Type

    • Plasma

    Gene Symbol

    • ZNF263

    UniProt ID

    • O14978

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