ZBT16

Isoform PLZFA of Zinc finger and BTB domain-containing protein 16;Zinc finger and BTB domain-containing protein 16

Acts as a transcriptional repressor (PubMed:10688654, PubMed:24359566). Transcriptional repression may be mediated through recruitment of histone deacetylases to target promoters (PubMed:10688654). May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • ZBTB16

UniProt ID

  • Q05516

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