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WWC2

Isoform 6 of Protein WWC2;Protein WWC2; Isoform 5 of Protein WWC2; Isoform 4 of Protein WWC2; Isoform 2 of Protein WWC2; Isoform 3 of Protein WWC2

Regulator of the Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway. Enhances phosphorylation of LATS1 and YAP1 and negatively regulates cell proliferation and organ growth due to a suppression of the transcriptional activity of YAP1, the major effector of the Hippo pathway.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • WWC2

    UniProt ID

    • Q6AWC2
    • Q6AWC2-3
    • Q6AWC2-4
    • Q6AWC2-5
    • Q6AWC2-6
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