WDR54

WD repeat-containing protein 54; Isoform 2 of WD repeat-containing protein 54

When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • WDR54

UniProt ID

  • Q9H977

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