Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • WASHC3

    UniProt ID

    • Q9Y3C0

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