UBP46

Isoform 3 of Ubiquitin carboxyl-terminal hydrolase 46;Ubiquitin carboxyl-terminal hydrolase 46; Isoform 4 of Ubiquitin carboxyl-terminal hydrolase 46

Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:19075014, PubMed:26388029). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • USP46

UniProt ID

  • P62068
  • P62068-4

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