TTK

Dual specificity protein kinase TTK; Isoform 2 of Dual specificity protein kinase TTK

Phosphorylates proteins on serine, threonine, and tyrosine (PubMed:18243099, PubMed:29162720). Probably associated with cell proliferation (PubMed:18243099). Phosphorylates MAD1L1 to promote mitotic checkpoint signaling (PubMed:29162720). Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint (PubMed:18243099).

Associated with:

G2M Checkpoint
Mitotic Spindle
Protein Phosphorylation
Spermatogenesis

Matrix Type

Tissue/Cells

Gene Symbol

UniProt ID

P33981

REQUEST ASSAY

Request the TTK Assay

Tell us a little more about your study so we can optimize the assay for your specific needs.

ASK A QUESTION

"*" indicates required fields

TTK

Dual specificity protein kinase TTK; Isoform 2 of Dual specificity protein kinase TTK

Associated with:

Matrix Type

Gene Symbol

UniProt ID

Request the TTK Assay

SERVICES

APPLICATIONS

PARTNERING

RESOURCES

ABOUT