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TT21B

Tetratricopeptide repeat protein 21B

Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Essential for retrograde trafficking of IFT-1, IFT-B and GPCRs (PubMed:27932497). Negatively modulates the SHH signal transduction (By similarity).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • TTC21B

UniProt ID

  • Q7Z4L5
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