Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • TSPYL5

    UniProt ID

    • Q86VY4

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