TOX4

TOX high mobility group box family member 4; Isoform 3 of TOX high mobility group box family member 4; Isoform 2 of TOX high mobility group box family member 4

Transcription factor that modulates cell fate reprogramming from the somatic state to the pluripotent and neuronal fate (By similarity). Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase (PubMed:20516061). In liver, controls the expression of hormone-regulated gluconeogenic genes such as G6PC1 and PCK1. This regulation is independent of the insulin receptor activation (By similarity).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • TOX4

    UniProt ID

    • O94842
    • O94842-3

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