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TOP2B

Isoform Beta-1 of DNA topoisomerase 2-beta;DNA topoisomerase 2-beta; Isoform Beta-1 of DNA topoisomerase 2-beta

Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. Plays a role in B-cell differentiation.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • TOP2B

UniProt ID

  • Q02880
  • Q02880-2
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