Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • THSD4

UniProt ID

  • Q6ZMP0

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