Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • TFPI

UniProt ID

  • P10646

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