TARA

Isoform 4 of TRIO and F-actin-binding protein; Isoform 1 of TRIO and F-actin-binding protein; Isoform 7 of TRIO and F-actin-binding protein; Isoform 3 of TRIO and F-actin-binding protein;TRIO and F-actin-binding protein;TRIO and F-actin-binding protein;Isoform 1 of TRIO and F-actin-binding protein

[Isoform 1]: Regulates actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin and prevents its depolymerization (PubMed:18194665, PubMed:28438837). May also serve as a linker protein to recruit proteins required for F-actin formation and turnover (PubMed:18194665). Essential for correct mitotic progression (PubMed:22820163, PubMed:24692559). ; [Isoform 5]: Plays a pivotal role in the formation of stereocilia rootlets. ; [Isoform 4]: Plays a pivotal role in the formation of stereocilia rootlets.

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • TRIOBP

    UniProt ID

    • Q9H2D6
    • Q9H2D6-3
    • Q9H2D6-5
    • Q9H2D6-7

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