TAF1C

TATA box-binding protein-associated factor RNA polymerase I subunit C; Isoform 2 of TATA box-binding protein-associated factor RNA polymerase I subunit C; Isoform 6 of TATA box-binding protein-associated factor RNA polymerase I subunit C

Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.

Associated with:

DNA Repair

Matrix Type

Tissue/Cells

Gene Symbol

TAF1C

UniProt ID

Q15572
Q15572-6

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TAF1C

TATA box-binding protein-associated factor RNA polymerase I subunit C; Isoform 2 of TATA box-binding protein-associated factor RNA polymerase I subunit C; Isoform 6 of TATA box-binding protein-associated factor RNA polymerase I subunit C

Associated with:

Matrix Type

Gene Symbol

UniProt ID

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